Which of the following would be the best tool for finding information about federal laws and regulations associated with water pollution?

The best tool for finding information about federal laws and regulations associated with water pollution is Lexis/Nexis Academic Universe. This database is specifically designed for legal research and contains a vast collection of legal documents, case law, regulations, and statutes. As water pollution is governed by numerous federal laws, such as the Clean Water Act, Lexis/Nexis provides access to primary sources, legal analyses, and comprehensive information about how these laws are applied and interpreted.

In contrast, the other options serve different purposes. Reader's Guide Full Text focuses primarily on indexing popular and scholarly articles across various subjects, making it less suitable for in-depth legal research. The World Almanac provides statistical and factual information on various topics but does not offer the specialized legal resources needed for this inquiry. Facts on File is a general reference resource that includes a variety of factual information but lacks the legal depth and specificity needed to navigate federal laws and regulations effectively. Therefore, Lexis/Nexis is the most appropriate choice for researching legal matters about water pollution.